Me too! It is all water level dependant. Ameren hosed up the Fall white run by dropping the lake 2.5' almost overnight during the first week of October. No idea why they did that, but we never got any precip to bring it back up and the White's reverted back to their typical summertime haunts...and are apparently still there as evidenced by Walleye13's post.
Once conditions are right this spring it will be water level dependant again, and I'll attempt to explain why.... When the lake is at normal full pool levels the silt and gravel that washes down the creeks settles and builds a hump on the flats, so when they suck the lake down it creates a 75-100 yard ankle deep hump that separates the lake from the tributary creeks. The Whites will not make that jump. A few might try but there are eagles and ospreys sitting there waiting for them to, so darn few actually make it.
In the Gravois, Glaize, Little Niangua, and the Buffalo's the magic number is 657.7
Regardless of how perfect the conditions are this spring you will not find a good number of Whites up in the creeks until the lake level gets up to that level. What typically happens is the weather and water temperature will be absolutely perfect, but the lake will still be down around 657-657.2, so there won't be anything worthwhile moving up in the creeks except for maybe a few walleye. But then we'll get a big gully washer and the lake will jump up 6-10". That opens the gate and finally the fun can begin.
If the rain event resulted in a full out flood, then as soon as things settle down enough that it is safe to get in the water you'll want to start at the 3rd riffle above the lake and work your way downstream. If it didn't really blow the creek out that bad then start just below the last riffle and work your way up.
Evenings, for whatever reason, are always best. From 4:pm until almost dark.
For the first week and a half to 2 weeks you'll catch mostly males, after that the girls will start showing up. When you start seeing alot of splashing around and fish waking just below the surface that is when the peak of the actual spawn is going on and you'll have several days when the fish are EVERYWHERE but you can't catch them worth a crap, and that'll drive you crazy. But that only lasts about 4-5 days, and after that little period they kinda spread out more, so instead of being able to stand in one spot and catch a limit in 30 minutes you'll have to move around and pick up 3-4 here and 2-3 there. They'll also start crushing topwater flys around that time.
The only other tip I can think to share right now is to strip those flys FAST. Slower retrieves hardly ever work as well as stripping it almost as fast and erratic as you can with very short pauses. If your stripping arm doesn't require a periodic rest every 15 minutes or so, and your wrist isn't aching, then you are fishing too slow.
I think that's all I got. Nothing to do now except tie fly's and wait.