It's easy to keep fresh chicken liver on a single hook, using a trick I learned at James A. Reed in the 1960s. Just run the hook through the liver lobe a couple or three times. Then wrap the liver moderately tightly about a dozen times with sewing thread. Cut the thread, and you're ready to cast. You can toss the liver a country mile without throwing it off the hook. Catfish don't seem to notice the thread; if anything, the thread absorbs blood and juices and tastes as good as the liver. To rebait, just snip off the old thread with a pair of scissors.
As for treble hooks, a single hook is usually one heck of a lot easier to remove from a catfish's throat.
I've used the brown-sugar trick with livers before, and it's deadly.