I prefer the Lake City area OTF. The road that takes you over Engineer Pass (towards Ouray) parallels Hanson Creek and you've got Lake San Cristobal that the Lake Fork of the Gunnison feeds and runs below with spectacular scenery (14'teeners) and good access.Head just east of Lake City towards Slugmillion Pass, not sure on the spelling there, then head north and there is some great brookie fishing up there.The Grand Mesa is the best place to haul a canoe or yak for stillwater fishing. Plenty of lakes (trout going airborne on Kastmasters) and the rivers are mostly wade stuff. I've had a blast up there. If you take the road to the Mesa off I-70 it's a heck of a beautiful drive. Check out the website "COLORADO DIRECTORY". Lots of info. Also, drive the "Million Dollar Highway" between Ouray and Silverton if you're in the area. You won't be disappointed. The areas I've mentioned are not near as crowded as Durango/Ouray/Silverton.
KC