Absolutely. Coachman trude, X-caddis, Cracklebacks, foam beetles, and my most recent favorite; Mercer's missing link are all really good on the Ni.
I'll leave sizes and colors out so as not to take all the fun out of it for ya, and to avoid assuming that the ones I like are the "best choice" there is.
The presence of any kind of "hatch" is irrelevant, and it does seem like the days when you can't keep the chubs off your drys is the perfect time to cut the dry off and throw a tan and brown muddler.