I think you are going to get a run of different answers depending on the particular strengths of who is fishing. For example...I would say an Eakins jig, Babbler will probably lean toward a jerkbait still about then, and another guy I know will be scrubbing a grub. Some early red fin or spook action might even be going on! Hard to say this far out as conditions are different every year.
As far as area....it will be preference again. If you look back at previous years....Bill says the Shell Knob area is best year round, I know another guy who never leaves the dam, Kelly Powers loves power fishing the James and so on. I know the Aunt's Creek area is really poor and no one should even consider going to that area.
People are probably weary of me saying this BUT if you are going to spend the time and effort to make a trip and fish, then a half day guide trip might not be a bad idea and help insure a more successful week of fishing.