I love how far you can cast with Nano but I have not found a leader knot that didn't fail when using it. I think Gavin brought up the triple surgeons. I used the alberto and the nano always broke on a hook set. I gave it two tries and gave up. I use 832 with the alberto and have never had a problem.
Might consider pepper spray as an option. The price is right for sure.
https://www.amazon.com/SABRE-RED-Pepper-Gel-Strength/dp/B004NKSPR8/ref=pd_lpo_vtph_421_tr_t_2?_encoding=UTF8&psc=1&refRID=538KTVX3C0PWB2D2MKFZ
I have a Smith and Wesson airweight in 38 special +P. Light, no fumbling around for a safety, no hammer to snag on clothes.
I believe it’s the most carried off duty pistol used by law enforcement.
Wouldn’t bother with a 380.