I lived in Spokane then Ozark and worked in and around Branson for about the last 20 years before I retired. No way would I want to actually live in or really close to Branson. I got so tired of driving around down there in town and to the places we took care of it was incredible. I wouldn't even go there for probably the first three years after laying it down.
To me it would be like living on The Strip at Lake of the Ozarks.
Doing the guide thing might be for you, I really don't know. If you make that plunge, I wish you the very best. The only thing I will suggest from my guided trips experience is provide absolute top shelf equipment. Nice big safe boat, always clean and ready to go. The best fishing equipment and plenty of it. Always on time is a given. But not to all sadly.
Good luck with whatever you do.