I fish up there all the time ( I live in Iowa) and it's a Bass fisherman's paradise. Bring plenty of buzz baits, frogs chatterbaits and jigs and Keitech 3.8 baits. I fish mostly in Pool 9 which is below LaCrosse, but it all fishes the same. The fish are out on the main channel along rock and near the various creeks and sleuths coming into the channel. Just be careful of the wing dams, stay outside of the channel markers and don't be running the shorelines. Wing dams will eat up your lower unit if you hit one. I attached a picture of a typical catch up there, with some running larger. September is a perfect time to go.